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Treatment of Stage III Melanoma That Cannot Be Removed By Surgery, Stage IV Melanoma, and Recurrent Melanoma

Treatment of stage III melanoma that cannot be removed by surgery, stage IV melanoma, and recurrent melanoma may include:

  • oncolytic virus therapy () injected into the tumor
  • immunotherapy with , , , , relatlimab, or interleukin-2 (IL-2), given alone or in combination
  • targeted therapy with signal transduction inhibitors (, , , , , ), given alone or in combination
  • chemotherapy
  • palliative therapy to relieve symptoms and improve the quality of life:
    • surgery to remove lymph nodes or tumors in the lung, digestive tract, bone, or brain
    • radiation therapy to the brain, spinal cord, or bone

Learn more about these treatments in the Treatment Option Overview.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

This information is not intended to replace the advice of a doctor. Navigating Care disclaims any liability for the decisions you make based on this information. This information was sourced and adapted from Adapted from the National Cancer Institute's Physician Data Query (PDQ®) Cancer Information Summaries on www.cancer.gov.

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